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刘永春教授
 

刘永春,男,汉族,1969910日出生,甘肃宁县人,中国共产党党员,甘肃省化学会会员,理学博士,教授,庆阳市环境影响评价审查专家库专家,现在陇东学院化学化工学院工作,主要从事生物无机化学及环境化学等方面研究工作,主讲无机化学、中级无机化学、化学专业英语、天然药物化学等课程。

主持完成“2016年甘肃省下达庆阳市革命老区环境保护项目项目(甘环规发[2016]1516号,庆环发〔2016166号,2016/05-2017/09)一项,主持完成甘肃省教育厅研究生导师科研计划项目两项(0510-062005/06-2008/121010B-042010/06-2012/12),参研完成国家自然科学基金项目(209750462010/01-2012/12)一项,2012年获甘肃省高校科技进步二等奖、2012年获第十九届甘肃省普通高等学校青年教师成才奖。先后发表本专业学术论文30余篇,其中SCIEI源刊收录论文19篇。

主要研究方向:

1、蛋白质-抗肿瘤植物药物偶联及药理学特性研究,药物剂型改进;

2、抗肿瘤金属配合物药物的合成及筛选;

3、用于扑灭油/烃火灾以及有机溶剂火灾的水成膜泡沫灭火剂研发与应用;

4、石油化工行业VOCs处置以及与排水相关的恶臭污染物处置、油污水处理等研究与应用。

代表性学术论文:

[1] Yong-Chun Liu*, Ying-Ying Li, Xiao-Jun Yao, Hui-Li Qi, Xiao-Xia Wei and Jian-Ning Liu. Binding Performance of Human Intravenous Immunoglobulin and 20(S)-7-Ethylcamptothecin [J]. Molecules, 2018, 23(9): 2389. (SCI)

[2] Yongchun Liu*, Yajun Li, Xiaojun Yao, Yingying Li, Huili Qi, Kejun Zhang, Ruixia Lei, Jianning Liu. Interaction of intravenous immunoglobulin and three 20(S)-camptothecin analogues: maintaining higher circulatory levels of the biologically active species [J]. Medicinal Chemistry Research, 2017, 26(12)3286–3295. (SCI)

[3] Yong-chun LIU*, Xiao-xia WEI, Xiu-ying XU, Xiao-jun YAO, Rui-xia LEI, Xu-dong ZHENG & Jian-ning LIU. Interaction of IVIG and Camptothecin [M]. In Medicine Sciences and Bioengineering (eds. Mings Wang), CRC press, 2015, ©2015 Taylor & Francis Group, London, UK, 551–557. (EI)

[4] 刘永春*,齐慧丽,魏晓霞,姚晓军,李莹莹,张克钧,刘建宁. 静注免疫球蛋白与盐酸伊立替康的相互作用[J]. 化学研究与应用,201527(12): 1841-1848. CSCD

[5] Yong-Chun Liu*, Ying-Ying Li, Hui-Li Qi, Ke-Jun Zhang, Rui-Xia Lei & Jian-Ning Liu. Crystal structures and DNA-binding properties of PrIIIcomplexes derived from 8-hydroxyquinoline-2-carboxaldehyde and three aroylhydrazines [J]. Journal of Coordination Chemistry, 2014, 67(22):3689–3703. (SCI)

[6] 刘永春*,徐秀英,雷瑞霞,张小伟,武芸,杨正银. La(III)配合物的抗氧化性和DNA结合性质研究[J].化学研究与应用,2013,25(11)1475-1483. CSCD

[7] Yongchun Liu*, Kejun Zhang, Ruixia Lei, Jianning Liu,Tianlin Zhou & Zheng-Yin Yang. DNA-binding and anti-oxidationproperties of binuclear lanthanide(III)complexes of 8-hydroxyquinoline-7-carbaldehyde-(isonicotinyl)hydrazone [J]. Journal of Coordination Chemistry, 2012, 65(12):20412054. (SCI)

[8] Yongchun Liu*, Kejun Zhang, Yun Wu, Junying Zhao, and Jianning Liu. Antioxidation and DNA-Binding Properties of Binuclear Lanthanide(III)Complexes with a Schiff Base Ligand Derived from 8-Hydroxyquinoline-7-carboxaldehyde and Benzoylhydrazine [J]. CHEMISTRY & BIODIVERSITY, 2012, 9:1533–1544. (SCI)

[9] Yongchun Liu*, Zhengyin Yang, Kejun Zhang, Yun Wu, Jihua Zhu and Tianlin Zhou. Crystal Structures, Antioxidation, and DNA BindingProperties of SmIII Complexes [J]. Australian journal of chemistry, 2011, 64, 345354. (SCI)

[10] Yong-chun Liu, Zheng-yin Yang*. Crystal structures, antioxidation and DNA binding properties of Eu(III) complexes with Schiff-base ligands derived from 8-hydroxyquinoline-2-carboxyaldehyde and three aroylhydrazines [J]. Journal of Inorganic Biochemistry, 2009, 103:1014–1022. (SCI)

[11] Yong-chun Liu, Zheng-yin Yang*. Crystal structure, antioxidation and DNA binding properties of binuclear Ho(III) complexes of Schiff-base ligands derived from 8-hydroxyquinoline-2-carboxyaldehyde and four aroylhydrazines [J]. Journal of Organometallic Chemistry, 2009, 694(19):3091–3101. (SCI)

[12]Yong-chun Liu, Zheng-yin Yang*. Crystal structures, antioxidation and DNA binding properties of Dy(III) complexes with Schiff-base ligands derived from 8-hydroxyquinoline-2-carboxaldehyde and four aroylhydrazines [J].European Journal of Medicinal Chemistry, 2009, 44(12):5080–5089. (SCI)

[13]Yong-chun Liu, Zheng-yin Yang*. Crystal structures, antioxidation and DNA binding properties of Yb(III) complexes with Schiff-base ligands derived from 8-hydroxyquinoline-2-carbaldehyde and four aroylhydrazines [J].Biometals, 2009, 22(5):733–751. (SCI)

[14]Yong-chun Liu, Zheng-yin Yang*.  Antioxidation and DNA binding properties of binuclear Nd(III) complexes with Schiff-base ligands derived from 8-hydroxyquinoline-2-carboxyaldehyde and four aroylhydrazides [J].Inorganic Chemistry Communications,2009, 12(8):704–706. (SCI)

[15] Yongchun Liu, Zhengyin Yang*, Juan Du, Xiaojun Yao, Ruixia Lei, Xudong Zheng, Jianning Liu, Huaisheng Hu, Hong Li. Interaction of curcumin with intravenous immunoglobulin: A fluorescencequenching and Fourier transformation infrared spectroscopy study [J]. Immunobiology,2008, 213:651–661. (SCI)

[16] Yongchun Liu, Zhengyin Yang*, Juan Du, Xiaojun Yao, Xudong Zheng, Ruixia Lei, Jianning Liu, Huaisheng Hu, Hong Li. Interaction of Taxol with intravenous immunoglobulin: An inhibition of Taxol from crystallizing in aqueous solution [J]. International Immunopharmacology, 2008, 8:390–400. (SCI)

[17] Yong-chun LIU, Zheng-yin YANG*, Juan DU, Xiao-jun YAO, Rui-xia, LEI,Xu-dong ZHENG, Jian-ning LIU, Huai-sheng HU, Hong LI. Study on the Interactions of Kaempferol and Quercetin with Intravenous Immunoglobulin by Fluorescence Quenching, Fourier Transformation Infrared Spectroscopy and Circular Dichroism Spectroscopy [J]. Chemical & Pharmaceutical Bulletin, 2008, 56(4):443–451. (SCI)

[18] Yongchun Liu, Ruixia Lei, Zhide Hu*, Xingguo Chen, Fengling Shen, Jing Jing. Studies on the binding of barbaloin to human gamma globulin [J]. Spectroscopy Letters, 2006, 39:265284. (SCI)

[19] Yongchun Liu, Wenying He, Wenhua Gao, Zhide Hu*, Xingguo Chen. Binding of wogonin to humangammaglobulin [J]. Int J Biol Macromol, 2005, 37:1−11. (SCI)

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